专利名称：IMPLANT SURFACES THAT ENHANCE
OSTEOINDUCTION
发明人：GALLAGHER, Michelle B.,BERG, Mark
E.,SCHNEIDER, Jennifer M.
申请号：EP17737707.4申请日：20170629公开号：EP3493768A1公开日：20190612
摘要：Bone-contacting surfaces and free surfaces of orthopedic implants. Theimplants are additively manufactured, followed by mechanical, chemical, or mechanicaland chemical erosion. At least some of the surfaces of the implants include an
osteoinducting roughness that has micro-scale structures and nano-scale structures thatfacilitate and enhance osteoinduction and osteogenesis, as well as enhanced alkalinephosphatase, osterix, and osteocalcin expression levels along the pathway ofmesenchymal stem cell differentiation to osteoblasts.
申请人：Titan Spine, Inc.
地址：6140 W. Executive Drive Mequon, WI 53092 US
国籍：US
代理机构：Locas, Davide
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